Species

J-VAC® 

Coliform Mastitis Vaccine 

 

Details

J-VAC® vaccine is a broad-spectrum bacterin-toxoid that protects against coliform mastitis caused by Escherichia coli and the effects of endotoxemia caused by E. coli and Salmonella Typhimurium.


It is approved for a whole-herd protocol and can be used for lactating cows, heifers or dry cows. 

Features & Benefits

Whole-Herd Protection

  • J-VAC® vaccine is the only vaccine of its kind approved for usage in the whole herd. 
  • In just two doses, J-VAC vaccine protects against coliform mastitis caused by E. coli and endotoxemia caused by E. coli and Salmonella Typhimurium. 
  • The unique TANDEM™ adjuvant in J-VAC vaccine keeps antigens in suspension, releases them over time, and stimulates enhanced immunity. 

Flexible Administration

  • J-VAC vaccine is easy to administer with a whole herd, two-dose protocol, and can reduce the incidence of clinical coliform mastitis cases by 81%.1 
  • Labeled for flexible administration, with intramuscular and subcutaneous injection-route options. 
     

 

Dosage & Administration

Administration 

  • For vaccination against coliform mastitis, inject one 2 mL dose intramuscularly or subcutaneously at seven months of gestation or at dry-off. Revaccinate one to three weeks before calving. Approved for whole-herd use. 

 

Timing 

  • For vaccination against the effects of endotoxemia, whole-herd vaccination may be done at any time. Vaccinate with one 2 mL dose followed by a second 2 mL dose two to four weeks later.
Resources

Product Inserts & Labels

J-VAC Product Label (PDF)
J-VAC SDS (PDF)

Safety

Precautions

  • Store away from heat or direct sunlight at 35-46ºF (2-8ºC).
  • Do not freeze.
  • Do not mix with other products.
  • Use entire contents when first opened.
  • Do not use chemicals to sterilize syringes or needles.
  • Do not vaccinate within 21 days before slighter.
  • In rare instances, administration of vaccines may cause lethargy, fever, and inflammatory or hypersensitivity types of reactions.
  • Treatment may include antihistamines, anti-inflammatories, and/or epinephrine.
  • In case of human exposure, contact a physician.
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J-VAC 2 Dose Protocol

Proven Efficacy. Two Doses.

In a field trial with more than 700 cows and heifers, two doses of J-VAC vaccine reduced the incidence of clinical coliform mastitis cases by 81 percent.1

Proven Efficacy. Two Doses.

In a field trial with more than 700 cows and heifers, two doses of J-VAC vaccine reduced the incidence of clinical coliform mastitis cases by 81 percent.1

J-VAC 2 Dose Protocol

Managing E. Coli Mastitis

Dr. Mark van der List, DVM, describes how to reduce the number of mastitis cases caused by E. coli on the dairy.

References

1 Data on file at Boehringer Ingelheim.

Trademarks

J-VAC® and the J-VAC logo® are registered trademarks of Boehringer Ingelheim Animal Health USA Inc. All other trademarks are the property of their respective owner. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. 

US-RUM-0028-2025