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Deworming Legends Header
Deworming Legends Header

Deworming Legends

Excellence is our signature.

This is more than a portfolio—it's a culmination of leadership. 

The first endectocide approved by the FDA, IVOMEC® 1% (ivermectin). The first topical endectocide, IVOMEC® Pour-On (ivermectin topical solution). The first endectocide with zero meat or milk withhold, EPRINEX® (eprinomectin). The first and only product to deliver up to 150 days of parasite control, LONGRANGE® (eprinomectin). The achievements go on and on.

All six brands have become powerhouses through decades of industry stewardship, reliance on research-backed data, and solid track records to boot. In other words, the stuff of legends. 

When it's time to choose a parasite control solution that accommodates your unique needs, choose a product from our lineup of Deworming Legends. This much experience makes all the difference.

Cattle Grazing in field

LONGRANGE (eprinomectin)

The first and only extended-release dewormer, with up to 150 days of parasite control.1

Cattle Grazing in field

EPRINEX (eprinomectin)

First pour-on dewormer with no meat or milk withdrawal.4

Cattle Grazing in field

IVOMEC (ivermectin)

A legendary family of products, including the first FDA approved cattle endectocide13, injectable with adult liver fluke control9 and pour-on to control biting and sucking lice.11

Cattle Grazing in field

SYNANTHIC (oxfendazole oral suspension)

First and only low-dose white drench dewormer.7

Region. Season. Hands on deck. No matter what you factor in, we've got a parasite control solution fit for the task.

LongRange eprinomectin bottles in different sizes for cattle parasite control, with green packaging.

LONGRANGE® (eprinomectin)

First and only extended-release dewormer

  • 11% higher average daily gains than yearling cattle treated with topical ivermectin.2
  • Increases pregnancy rates and shortens calving intervals, meaning more calves are born earlier, giving them more time to gain.3
  • Delivers a better return per head, and we’ve got the numbers to prove it.2,3
Learn more

LONGRANGE® (eprinomectin)

First and only extended-release dewormer

  • 11% higher average daily gains than yearling cattle treated with topical ivermectin.2
  • Increases pregnancy rates and shortens calving intervals, meaning more calves are born earlier, giving them more time to gain.3
  • Delivers a better return per head, and we’ve got the numbers to prove it.2,3
Learn more
LongRange eprinomectin bottles in different sizes for cattle parasite control, with green packaging.

LONGRANGE IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of slaughter. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, or in veal calves. Post-injection site damage (e.g., granulomas, necrosis) can occur. These reactions have disappeared without treatment. Not for use in breeding bulls, or in calves less than 3 months of age. Not for use in cattle managed in feedlots or under intensive rotational grazing. Pregnant women should wear gloves and exercise caution or avoid handling this product.

All of the sizes of Eprinex in a line

EPRINEX® (eprinomectin)

Pour on the pounds.

  • Pour-on dewormer that kills 39 species and stages of parasites.4
  • Proven to pack on an additional 36 pounds per head (P < 0.05) over 105 days in weaned calves vs. untreated controls.5
  • No milk or meat withhold and safe for use in dairy cattle.
  • Nonflammable, weatherproof formula that remains effective regardless of exposure to the elements and variation in coat length.
  • Convenient for processing large or small herds, and available in sizes ranging from 250mL up to 20L.
Learn more

EPRINEX® (eprinomectin)

Pour on the pounds.

  • Pour-on dewormer that kills 39 species and stages of parasites.4
  • Proven to pack on an additional 36 pounds per head (P < 0.05) over 105 days in weaned calves vs. untreated controls.5
  • No milk or meat withhold and safe for use in dairy cattle.
  • Nonflammable, weatherproof formula that remains effective regardless of exposure to the elements and variation in coat length.
  • Convenient for processing large or small herds, and available in sizes ranging from 250mL up to 20L.
Learn more
All of the sizes of Eprinex in a line

EPRINEX IMPORTANT SAFETY INFORMATION: No meat or milk withdrawal is required when used according to label. Do not use in calves intended for veal or unapproved animal species, as severe adverse reactions, including fatalities in dogs may result.

All of the Synanthic products in a row

SYNANTHIC® (oxfendazole oral suspension)

Low-dose, white dewormer that controls multiple stages of stomach worms, intestinal worms, lungworms and tapeworms.

  • Fast-acting, reaches peak potency within 20 hours.6
  • Works in one highly concentrated, highly effective dose of 1 mL per 110 lbs. body weight.7
Learn more

SYNANTHIC® (oxfendazole oral suspension)

Low-dose, white dewormer that controls multiple stages of stomach worms, intestinal worms, lungworms and tapeworms.

  • Fast-acting, reaches peak potency within 20 hours.6
  • Works in one highly concentrated, highly effective dose of 1 mL per 110 lbs. body weight.7
Learn more
All of the Synanthic products in a row

SYNANTHIC IMPORTANT SAFETY INFORMATION: Residue Warnings: Cattle must not be slaughtered until 7 days after treatment. Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age.

Ivomec Plus Product Family

IVOMEC® PLUS (ivermectin and clorsulon)

The original fluke fighter.

  • Controls more than 30 species and stages of external and internal parasites, including adult liver flukes.8
  • Cattle treated for liver flukes have shown a higher average daily gain than those treated only for internal and external parasites.9
  • Kills more stages and species of parasites than Valbazen® (albendazole oral suspension).10
Learn more

IVOMEC® PLUS (ivermectin and clorsulon)

The original fluke fighter.

  • Controls more than 30 species and stages of external and internal parasites, including adult liver flukes.8
  • Cattle treated for liver flukes have shown a higher average daily gain than those treated only for internal and external parasites.9
  • Kills more stages and species of parasites than Valbazen® (albendazole oral suspension).10
Learn more
Ivomec Plus Product Family

IVOMEC PLUS IMPORTANT SAFETY INFORMATION: Do not treat cattle within 21 days of slaughter. Do not use in female dairy cattle of breeding age or in veal calves. Do not use in other animal species not on the label, as severe adverse reactions, including fatalities in dogs, may result.

Ivomec Family

IVOMEC® 1% (ivermectin)

The first cattle endectocide approved by the FDA.

  • IVOMEC 1%  injection dewormer effectively controls more than 30 species and stages of internal and external parasites. 
Learn more

IVOMEC® 1% (ivermectin)

The first cattle endectocide approved by the FDA.

  • IVOMEC 1%  injection dewormer effectively controls more than 30 species and stages of internal and external parasites. 
Learn more
Ivomec Family

IVOMEC 1% IMPORTANT SAFETY INFORMATION: Do not treat cattle within 35 days of slaughter. Do not use in female dairy cattle of breeding age or in veal calves. Do not treat swine within 18 days of slaughter. Do not use in other animal species not on the label, as severe adverse reactions, including fatalities in dogs, may result.

Product shot of all the Ivomec Pour On Sizes

IVOMEC® Pour-On (ivermectin topical solution)

Broad-spectrum dewormer with proven protection, efficacy, and duration.

  • Time-tested control of more than 30 species and stages of internal and external parasites.11
  • Effective fly and lice control.
  • Convenient pour-on formulation.
  • Studies show that IVOMEC POUR-ON dewormer delivers significantly more average daily gains than generics.12
Learn more

IVOMEC® Pour-On (ivermectin topical solution)

Broad-spectrum dewormer with proven protection, efficacy, and duration.

  • Time-tested control of more than 30 species and stages of internal and external parasites.11
  • Effective fly and lice control.
  • Convenient pour-on formulation.
  • Studies show that IVOMEC POUR-ON dewormer delivers significantly more average daily gains than generics.12
Learn more
Product shot of all the Ivomec Pour On Sizes

IVOMEC POUR-ON IMPORTANT SAFETY INFORMATION: Do not treat cattle within 48 days of slaughter. Do not use in female dairy cattle of breeding age or in veal calves. Do not use in other animal species not on the label, as severe reactions, including fatalities in dogs, may result.

The game has evolved. Has your game plan?

Parasites are catching on. Outsmart them with a balanced, resourceful plan of attack. One that incorporates the following four pillars of sustainable deworming:

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Diagnostics

Monitor deworming efficacy with ongoing surveillance and routine diagnostic testing.

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Combination Treatment

Using two or more dewormers from different drug classes with different modes of action to reduce the amount of parasite survivors.

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Refugia

Portion of the parasite population not exposed to selection pressure. Parasites are left in "refuge" from the dewormer. Consult with your veterinarian.

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Management

Forage height, pasture management, stocking density, overgrazing and rotation impact deworming programs.

References

1Dependent on parasite species, as referenced in FOI summary and LONGRANGE product label.

2Rademacher RD, Behlke EJ, Parr SL, et al. An evaluation of eprinomectin extended-release injectable (LongRange®) on the performance of yearling cattle on pasture in western Canada. Bov Pract 2018;52(1):46–52.

3Andresen CE, Loy DD, Brick TA, Gunn PJ. Case study: Effects of extended-release eprinomectin on cow-calf performance and reproductive success in a fall-calving beef herd. Prof Anim Sci 2018;34(2):223–229.

4Based on EPRINEX label claims and FOI summary.

5Beckett JL. Efficacy of pour-on dewormers differing in active ingredient and carrier on weight gain and fecal egg count in stocker beef cattle. College of Agriculture, Cal Poly State University. 2000.

6Pritchard, R.K., et. Al. Research in Veterinary Science. 29:173-178. 1985.

7Based on SYNANTHIC label claims and FOI summary.

8Based on IVOMEC PLUS label claims and FOI summary.

9Marley SE, Corwin RM, Hutcheson DP. Effect of Fasciola hepatica on productivity of beef steers from pasture through feedlot. Agri-Practice 1996;17:18–23.

10Valbazen 11.36% Drench product label.

11Based on IVOMEC POUR-ON label claims and FOI summary.

12Yazwinski TA, et al. A field trial evaluation of several commercial Ivermectin pour-on products in cattle. Ark Cattle Bus 2004;20(9):44–46.

13Based on IVOMEC 1% label claims and FOI summary.

 

EPRINEX®, IVOMEC®, LONGRANGE®, SYNANTHIC® and the Cattle Head Logo® are registered trademarks of Boehringer Ingelheim Animal Health USA Inc. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. US-RUM-0079-2025

LONGRANGE IMPORTANT SAFETY INFORMATION: Do not treat within 48 days of slaughter. Not for use in female dairy cattle 20 months of age or older, including dry dairy cows, or in veal calves. Post-injection site damage (e.g., granulomas, necrosis) can occur. These reactions have disappeared without treatment. Not for use in breeding bulls, or in calves less than 3 months of age. Not for use in cattle managed in feedlots or under intensive rotational grazing. Pregnant women should wear gloves and exercise caution or avoid handling this product.​