CALVENZA®-03 EIV/EHV

Equine Rhinopneumonitis - Influenza Vaccine

Details

  • CALVENZA®-03 EIV/EHV is an equine rhinopneumonitis and influenza, killed virus vaccine for healthy horses 6 months of age or older, including pregnant mares, against:
    • respiratory diseases due to equine herpesvirus types 1 and 4 (EHV-1 & EHV-4)
    • equine influenza virus (EIV) types A2 North American and A2 Eurasian
  • The first equine influenza vaccine updated to follow World Organisation for Animal Health (WOAH) guidelines to contain Florida sublineage clade 1
  • Flexible administration - Give first and second doses IM at different injection sites; third dose may be given IM or IN. Allow 3–4 weeks between doses.
Features & Benefits

Features

  • Incorporates Florida sublineage clade 1 (OH/03), Kentucky (KY/2/95), and Eurasian Newmarket/2/93 (NM/2/93) equine influenza strains
  • Unique EHV-1 equine respiratory origin isolate
  • CARBIMMUNE® adjuvant formulation
  • ULTRAFIL™️ purification technology
  • Includes innovative pliable nasal applicator
  • Safe for use in foals as young as 6 months of age
  • Proven safe in pregnant mares

Benefits

  • Stimulates antibody production against EHV-1 & EHV-4
  • CARBIMMUNE® adjuvant system allows a dual-phase antigen presentation to deliver both rapid and long-lasting immunity
  • ULTRAFIL™️ purification technology eliminates undesirable cellular components and extraneous protein to minimize the potential injection site reactions (such as heat, swelling, and inflammation)
  • Flexible dose administration using intramuscular or intranasal techniques
  • Pregnant mare may be safely vaccinated in any stage of gestation
  • Can initiate vaccination in foals as early as 6 months of age
Dosage & Administration

Shake the bottle well before using.  Using aseptic technique, inoculate horses intramuscularly (IM) with a 2mL dose.

Administer second 2mL dose IM in 3-4 weeks using a different injection site.

Administer a third 2mL dose in 3-4 weeks either by intramuscular or intranasal (IN) route.

 

The need for annual booster vaccinations has not been established for this product; consultation with a veterinarian is recommended.

Resources
Safety Information

Precautions

  • Store at a temperature between 35° - 46°F (2° - 8°C)
  • Do not freeze
  • Do not vaccinate within 21 days of slaughter
  • Do not mix with other products
  • Use entire contents after opening

 

In case of anaphylactoid reaction, administer epinephrine. In case of human exposure, contact a physician.

 

Trademarks

CALVENZA® is a registered trademark of Boehringer Ingelheim Vetmedica GmbH, used under license. CARBIMMUNE® is a registered trademark and ULTRAFIL™️ is a trademark of Boehringer Ingelheim Animal Health USA Inc. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. US-EQU-0105-2021-V2