INGELVAC CIRCOFLEX®AD

Porcine Circovirus Type 2 Vaccine (Killed Baculovirus Vector) 

Details

INGELVAC CIRCOFLEX® AD is the first PCV2 vaccine to confer homologous protection against both PCV2a and PCV2d, and to contain both antigens in its composition.1,2 Built on the trusted foundation of INGELVAC CIRCOFLEX®, INGELVAC CIRCOFLEX AD provides producers with an additional choice against evolving PCV2 threats, offering high-performance protection while maintaining the flexibility producers have come to rely on. 

 

Complete 

Dual-genotype antigens of PCV2a and PCV2d provide broad protection against evolving PCV2 threats.

 

Efficacious 

Delivers robust protection in a single, 1-mL dose, as demonstrated by significantly reduced lymphoid depletion and colonization, as well as significantly reduced viremia.2 

 

Safe 

Powered by the IMPRANFLEX® adjuvant, INGELVAC CIRCOFLEX AD provides safe, full production cycle immunity with a demonstrated low risk of adverse reactions. 

Features & Benefits

  • Contains both PCV2a and PCV2d antigens in its composition, providing broad coverage against the most relevant genotypes in circulation1,2 

 

  • Single dose injection that reduces labor costs compared to two-dose vaccines and minimizes stress on pigs 

 

  • Low viscosity, highly syringeable 

 

  • Low risk of adverse reactions and stress on pigs due to one-dose administration and IMPRANFLEX adjuvant (an effective, aqueous-based [non-oil] polymer adjuvant) 

 

  • At least 26 weeks of protection and onset of immunity within two weeks of vaccination 

 

  • Highly immunogenic and non-virucidal vaccine that is clear in color, thanks to a state-of-the-art and novel purification process 

 

  • Member of the FLEX Family (10 swine vaccines, multiple combinations); allows for flexible vaccination scheduling

     

Dosage & Administration

  • Shake well before use

 

  • Using aseptic technique, administer a single 1-ml dose by intramuscular injection 

 

  • Does not need to be tempered
Resources
Safety

INGELVAC CIRCOFLEX AD Safety Data Sheet (SDS) 

 

  • Store in the dark at 35–46°F (2–8°C) 
  • Do not freeze 
  • Use entire contents when first opened 
  • Do not vaccinate within 21 days of slaughter 
  • In case of anaphylactic reaction, epinephrine is a symptomatic treatment 
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IMPRANFLEX® Adjuvant

IMPRANFLEX is a proprietary water-based, sponge-like matrix adjuvant found in all FLEX Family vaccines that offers the following advantages:  

  • Does not contain and is not derived from any material of plant or animal origin
  • 100 percent oil free 
  • Low viscosity and good syringeability 
  • Very safe for farm staff and animals 
  • Less stressful for the animals  
  • Non-virucidal to PRRSV
INGELVAC CircoFLEX AD product image with a galaxy around it

The newest member of the FLEX family

INGELVAC CIRCOFLEX AD is the latest innovation from the trusted Boehringer Ingelheim FLEX Family — the name producers have relied on for nearly two decades of PCV2 protection. Now with an enhanced formulation that includes both PCV2a and PCV2d antigens for dual-genotype protection, it gives producers more flexibility and confidence to protect their pigs, profits and future.

 

The newest member of the FLEX family

INGELVAC CIRCOFLEX AD is the latest innovation from the trusted Boehringer Ingelheim FLEX Family — the name producers have relied on for nearly two decades of PCV2 protection. Now with an enhanced formulation that includes both PCV2a and PCV2d antigens for dual-genotype protection, it gives producers more flexibility and confidence to protect their pigs, profits and future.

 

INGELVAC CircoFLEX AD product image with a galaxy around it
References

 

1Franzo G, Tucciarone CM, Legnardi M, Drigo M, Segalés J. An updated phylogeography and population dynamics of porcine circovirus 2 genotypes: are they reaching an equilibrium? Front Microbiol 2024;15:1500498. doi: 10.3389/fmicb.2024.1500498.   

 

2Kaiser T, Jarrett A, Hinds M, Leite F. Efficacy of a novel vaccine containing both PCV2a and PCV2d antigens, in Proceedings. 2025 Allen D. Leman Swine Conference. 

Trademarks

INGELVAC CIRCOFLEX® and IMPRANFLEX® are registered trademarks of Boehringer Ingelheim Vetmedica GmbH, used under license. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. 

US-SWN-0004-2025-V2