3FLEX®

Porcine Circovirus Type 2 (PCV2), Mycoplasma hyopneumoniae (Mhp) and Porcine Reproductive and Respiratory Syndrome (PRRS) Vaccine 

Details

FLEXIBLE 3-IN-1: The only single-dose, three-way vaccine licensed by the USDA for use in swine to control PCV2, Mhp and PRRS. 

 

EFFECTIVE: Extensive research studies show that 3FLEX consistently provides effective protection against clinical disease associated with PCV2, Mhp and PRRS. 

 

SAFE: Strong immune response and low risk of adverse reactions.

Features & Benefits

  • Single dose that reduces labor costs compared to two-dose vaccine and minimizes stress on pigs.

     

  • Low viscosity, highly syringeable.

     

  • Low risk of adverse reactions and stress on pigs due to one-dose administration and IMPRANFLEX® adjuvant (an effective, aqueous-based [non-oil] polymer adjuvant).

     

  • Long-lasting duration of immunity and rapid onset of immunity.

     

  • Highly immunogenic and non-virucidal vaccine, thanks to a state-of-the-art and novel purification process (DiaTEC).

     

  • A member of the FLEX Family (10 swine vaccines, multiple combinations); allowing you flexible vaccination scheduling.
Dosage & Administration

  • Mix the package contents according to label instructions. 

     

  • Using aseptic technique, inject a single 2-mL dose of vaccine intramuscularly. 

     

  • Does not need to be tempered. 

     

  • Headspace bottle (HSB) technology allows for easy mixing.

 

3FLEX mixing instructions infographic

 

3FLEX Mixing Video - English

3FLEX Mixing Video - Spanish

Resources
Safety

3FLEX Safety Data Sheet (SDS)

 

  • Store in dark at 35-46ºF (2-8ºC). 
  • Do not freeze. 
  • Use entire contents when first opened. 
  • Do not vaccinate within 21 days before slaughter. 
  • In case of anaphylactic reaction, epinephrine is symptomatic treatment. 
  • Do not vaccinate boars. 
  • Indicated for use in PRRS virus–positive herds only. PRRS vaccine virus may be shed and transmitted to other populations of swine that are in contact with vaccinated swine.

 

3FLEX® Mixing Video

3FLEX vaccine is available with headspace bottle (HSB) technology. Follow these instructions for easy mixing and administration.

3FLEX® Mixing Video in Spanish

PrimaTech® – Neogen® Needle

The PrimaTech – Neogen transfer needle is complimentary for FLEXCOMBO® and 3FLEX 250-dose and 50-dose vaccine presentations.  To request transfer needles or for more information about which needle to use, please contact your Boehringer Ingelheim key account manager. 

PrimaTech Neogen Transfer Needle Image
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IMPRANFLEX® Adjuvant

IMPRANFLEX is a proprietary water-based, sponge-like matrix adjuvant found in all FLEX Family vaccines that offers the following advantages:  

  • Does not contain and is not derived from any material of plant or animal origin
  • 100 percent oil free 
  • Low viscosity and good syringeability 
  • Very safe for farm staff and animals 
  • Less stressful for the animals  
  • Non-virucidal to PRRSV

DiaTEC and IMPRANFLEX – a perfect combination

The Boehringer Ingelheim DiaTEC process is a unique, patented diafiltration process that removes residual cell media components from the antigens, or virus-like particles (VLPs), in the vaccine, resulting in a non-virucidal vaccine. And thanks to this state-of-the-art purification process, INGLEVAC CIRCOFLEX is now non-virucidal, easing the mixing process with modified-live INGELVAC PRRS MLV when using 3FLEX. DiaTEC and IMPRANFLEX work together to offer the following advantages:  

  •  Strong efficacy for full cellular protection  
  • Safe for sows and piglets  
  • Rapid onset and long-lasting immunity   
  • Depot effect  
  • Three antigens in one shot
Trademarks

3FLEX®, INGELVAC CIRCOFLEX®, INGELVAC MYCOFLEX®, INGELVAC PRRS®, FLEXCOMBO® and IMPRANFLEX® are registered trademarks of Boehringer Ingelheim Vetmedica GmbH, used under license. All other trademarks are the property of their respective owner. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved. 

US-SWN-0020-2025