Unlike fleas and ticks, pet owners can’t see the effects of heartworm disease until it’s too late. Educate clients on proper prevention followed by a recommendation of HEARTGARD® Plus (ivermectin/pyrantel).
Heartworm Disease
HEARTGARD Plus chews attack and eliminate heartworm larvae transmitted by…
HEARTGARD Plus chews attack and eliminate heartworm larvae transmitted by an infected mosquito before larvae can grow into adults.
3 Species of Hookworms
Hookworms are the second most prevalent intestinal nematode parasites in dogs.†4…
Hookworms are the second most prevalent intestinal nematode parasites in dogs.†4 HEARTGARD Plus chews are indicated for the treatment and control of the 3 most prevalent species of hookworms in the US: Ancylostoma caninum, Uncinaria stenocephala, and Ancylostoma braziliense.
2 Species of Roundworms
Roundworms are the most common intestinal nematode parasites in dogs†4…
Roundworms are the most common intestinal nematode parasites in dogs and cats in the world.†4 HEARTGARD Plus chews are indicated for the treatment and control of Toxocara canis and Toxascaris leonina in dogs.
PRODUCT OVERVIEW
HEARTGARD Plus chews prevent heartworm disease as well as treat and control hookworms and roundworms. HEARTGARD Plus is delivered in a real-beef chew that dogs prefer.*3
Use monthly to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of hookworms (Ancylostoma caninum, Uncinaria stenocephala, and A. braziliense) and roundworms (Toxocaracanis and Toxascaris leonina).
FEATURES & BENEFITS
- Once-a-month real-beef chew that dogs prefer*3
- #1 vet-recommended heartworm disease preventive5
- #1 dog-preferred heartworm disease preventive*3
- The heartworm preventive in HEARTGARD Plus chews has been trusted over 2 billion times2
- Safe for puppies 6 weeks of age or older with no minimum weight requirement
- The dose of ivermectin in HEARTGARD Plus chews is essentially excreted in 72 hours6
- Treats and controls 3 species of hookworms and 2 species of roundworms
- HEARTGARD Plus chews offer the HEARTGARD Plus Satisfaction Guarantee
DOSAGE & ADMINISTRATION
Remove only 1 chew at a time from the foil-backed blister card. Return the card with the remaining chews to its box to protect the product from light. Because most dogs find HEARTGARD Plus chews palatable, the product can be offered to the dog by hand. Alternatively, it may be added intact to a small amount of dog food. The chew should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chews may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose. Treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the chew has been lost, redosing is recommended.
Dosage Chart
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For dogs over 100 lbs, give the appropriate combination of chews once a month.
SAFETY
For dogs 6 weeks of age and older with no minimum weight requirement.
IMPORTANT SAFETY INFORMATION: HEARTGARD Plus is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurologic side effects have been reported. For more information, click here for full prescribing information.
Pet Owner Resources
Fact Sheet
Clinic Education
References
*For dogs demonstrating a preference, they preferred HEARTGARD Plus chews over the competition.
†GI nematodes only.
- Data on file at Boehringer Ingelheim.
- Data on file at Boehringer Ingelheim.
- Data on file at Boehringer Ingelheim.
- AVMA. Internal Parasites in Cats and Dogs. Accessed September 15, 2022. https://ebusiness.avma.org/files/productdownloads/internalparasites_brochure.pdf
- Data on file at Boehringer Ingelheim.
- Daurio CP, Cheung EN, Jeffcoat AR, Skelly BJ. Bioavailability of ivermectin administered orally to dogs. Vet Res Comm. 1992;16(2):125-130.
Trademarks
HEARTGARD® and the Dog & Hand logo® are registered trademarks of Boehringer Ingelheim Animal Health USA Inc. All other trademarks are the property of their respective owner. ©2026 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved.
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